Berberine

Adenosine Mono-Phosphate Kinase is an essential enzyme in balancing the energy balance. Both at the cellular level and in the human body as a whole, AMPK is at the center of studies on obesity, diabetes and metabolic syndrome. Active in energy homeostasis, adenosine Mono-Phosphate Kinase is activated by berberine.

Berberine is an alkaloid extracted from various plants including Berberis vulgaris, commonly called barberry. Thanks to its hypoglycemic effects, this food supplement constitutes an interesting aid in the treatment of people who suffer from type II diabetes. 

Berberine indications

• Energy activation;

• Balance of sugar metabolism;

• Fat storage regulation;

• Overweight (obesity) problem;

• Reduces the risk of brain degeneration;

• Helps protect the intestinal wall. 

Berberine is naturally found in certain plants such as Berberis aristata, a shrub from the Himalayan region and Nepal, Argemone mexicana, Berberis vulgaris (barberry) or Hydrastis canadensis. The latter two are known in homeopathy. Berberine has been used for millennia in the pharmacopoeia of traditional Chinese and Ayurvedic medicine because of its many properties and benefits for well-being.

Its numerous therapeutic indications are beneficial in various areas of health. Berberine is multi-potential because it therefore acts at different stages, for example as an antifungal and anti-inflammatory. But its main actions are found in intestinal repair and the ability of cells to absorb glucose. Berberine is then a food supplement very appreciated by people with diabetes thanks to its hypoglycemic power. Indeed, it greatly lowers blood sugar.

Bowel disorders and berberine

The consumption of refined sugars is a disaster for health. In addition to damage to the liver, intestinal absorption is reduced by a partial or total degradation of the intestinal mucosa. In addition to the blood sugar level well known by people with diabetes, these eating disorders cause serious damage to health.

Many diseases have their sources in intestinal discomfort. The porous intestines are the cause of various disorders in the health field. The pharmacist, naturopath or health practitioner generally prescribes or advises probiotics hoping to reseed damaged soil. However, the priority comes to repairing the intestine. Probiotics in case of porosity are useless. Berberine acts as a field repair agent to repair intestinal permeability. So, tissue regeneration will be effective by the positive action of berberine on the intestinal epithelium. 

Berberine then protects the intestinal ecosystem against leaky-gut, colitis and even food allergies. Indeed, many allergies find their source within the intestine.

The beneficial effects for the body and the well-being of berberine

Recent research shows spectacular effects on the metabolism of sugars, fatty acids and on general energy, but also on the elimination of toxins by the filtering organs and by the emunctories. 

Berberine and AMPK

Berberine facilitates the activation of AMPK (Adenosine Mono-Phosphate Kinase), a molecule that plays a vital role in energy balance. This has a direct impact on the oxidation of fatty acids and therefore on cholesterol and triglycerides, as well as on the processing and storage of sugars and dietary carbohydrates. The enzymes responsible for all stages of carbohydrate metabolism will be more efficient and more active. As a result, sugars and carbohydrates will be better transported and used better, which will prevent development, reduce and / or alleviate certain health problems related to the resistance, use and storage of carbohydrates. All this can be measured by a simple blood test.Berberine is studied to try to stop the "pandemics" linked to the problems of overweight of a very large part of the current population. Its effects have been shown to be equivalent to, and sometimes even superior to, that of certain chemical molecules commonly used to regulate carbohydrate problems.

Berberine and the treatment of diabetes

By activating AMPK, berberine increases the expression of the GluT-4 gene, a transporter of muscle and adipocyte glucose, it facilitates the transport of intracellular glucose and makes it possible, by improving insulin sensitivity, to reduce the blood sugar. Berberine has been studied as an adjuvant in type 2 diabetes, with results equivalent to, and sometimes even superior to, those of metformin. A recent study, carried out on 116 patients with type 2 diabetes randomized to receive 1g / d of berberine or a placebo for 3 months showed a reduction in the carbohydrate parameters: an HbA1c which goes from 7.5% to 6.6% and a reduction in fasting blood sugar from 126 to 100.8 mg / dl. 

Berberine and cardiovascular disease

Berberine cooperates in the inhibition of the synthesis of fatty acids and contributes to reducing the circulating lipids levels (LDL cholesterol). This action is easily assessed by the cholesterol levels which improve when taking this substance. 

Berberine helps reduce fatty deposits throughout the body, which provides natural protection against major problems and well-being. It seems obvious that when everything is going well, all of the cellular processes improve. 

Berberine and its action on cognitive functions

From a nervous point of view, berberine helps protect cognitive functions and mental faculties. It facilitates the balance of sad and gloomy moods, while reducing the risks of nervous degenerations (accompanied among others by memory loss, balance disorders, tremors, etc.) which are very common in the aging populations of our time. . 

Another benefit of berberine applies to the digestive tract, because it protects the wall, which limits food sensitivities or intolerances, as well as intestinal discomfort that can result from these hypersensitivities. 

Berberine and metabolic syndrome

Berberine can also be a valuable support and support in larger body problems, as it helps the body to stop the development of abnormal cells. 

The Zell-Screning is a device that measures deficiencies or excess vitamins, minerals and heavy metals. An excess of zinc (often accompanied by high levels of copper) which, according to doctors, can be a sign of inflammation and / or a significant liver problem not related to alcohol (diagnosis to be confirmed by a doctor). These problems often occur in people who are overweight, have sugar metabolism disorders, or have high cholesterol and triglyceride levels. Taking a dose of 500 mg of berberine 3 times a day for 6 weeks helps to correct these excessively high zinc levels.

In addition to its therapeutic health benefits, berberine plays an important role in fat storage. Thanks to the enzymatic stimulation of AMPK, the body under berberine avoids fat storage in the body. Lipids and carbohydrates are more easily transformed into energy beneficial for health. Berberine is one of the interesting dietary supplements in the search for weight loss.

The consumption of the berber plant will not be sufficient for therapeutic virtues. 50 kg of berberis are essential to extract 1 kg of berberine. Do not consume as many plants with each meal. Prefer the capsules, more suitable.